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Knowledge Update

Introduction & Purpose
Knowledge update and Industry update at Skyline University College (SUC) is an online platform for communicating knowledge with SUC stakeholders, industry, and the outside world about the current trends of business development, technology, and social changes. The platform helps in branding SUC as a leading institution of updated knowledge base and in encouraging faculties, students, and others to create and contribute under different streams of domain and application. The platform also acts as a catalyst for learning and sharing knowledge in various areas.

Poor sleep may lead to behavioural problems

New York, March 12 (IANS) Children between age 3 and 7 who do not get enough sleep are more likely to have problems with attention, emotional control and peer relationships, says a study.

"We found that children who get an insufficient amount of sleep in their pre-school and early school-age years have a higher risk of poor neuro-behavioral function at around age 7," said lead researcher Elsie Taveras from the MassGeneral Hospital for Children in the US.

"The associations between insufficient sleep and poorer functioning persisted even after adjusting for several factors that could influence the relationship," Taveras said.

As in previous studies from this group examining the role of sleep in several areas of child health, the current study analysed data from Project Viva, a long-term investigation of the health impacts of several factors during pregnancy and after birth.

Information used in this study was gathered from mothers at in-person interviews when their children were around 6 months, 3 years and 7 years old, and from questionnaires completed when the children were aged 1, 2, 4, 5 and 6 years.

In addition, mothers and teachers were sent survey instruments evaluating each child's executive function - which includes attention, working memory, reasoning and problem solving -- and behavioural issues -- including emotional symptoms and problems with conduct or peer relationships, when children were around 7.

Among 1,046 children enrolled in Project Viva, the study team determined which children were not receiving the recommended amount of sleep at specific age categories -- 12 hours or longer at ages 6 months to 2 years, 11 hours or longer at ages 3 to 4 years, and 10 hours or longer at 5 to 7 years.

The study, published online in the journal Academic Pediatrics, found significant differences in the responses of parents and teachers to surveys regarding executive function and behavioural problems in 7-year-old children depending on how much sleep they regularly got at younger ages.

High-intensity aerobic training may help reverse ageing

New York, March 11 (IANS) High-intensity aerobic exercise may be the best type of training for people over 65, as it can reverse some cellular aspects of ageing, an Indian-origin researcher has found. The findings showed that high-intensity interval training (or cardio) like running and walking, improved muscle protein content enhancing energetic functions and causing muscle enlargement, especially in older adults. "We encourage everyone to exercise regularly, but the take-home message for ageing adults is that supervised high-intensity training is probably best,"said K. Sreekumaran Nair, Indian-origin endocrinologist at the Mayo Clinic, a non-profit health care research organisation. Nair explained that this kind of training helped both metabolically and at the molecular level, confering the most benefits. Decline in mitochondrial content and function are common in older adults. The high-intensity exercise regimen significantly enhanced the cellular machinery responsible for making new proteins, contributing to synthesis, thus reversing a major adverse effect of ageing. While high-intensity training reversed some manifestations of ageing in the body's protein function, adding resistance training may also help achieve significant muscle strength, Nair added. In the study, appearing in the journal Cell Metabolism, the team compared high-intensity interval training, resistance training and combined training. Researchers tracked metabolic and molecular changes in a group of young and older adults over 12 weeks, gathering data 72 hours after individuals in randomised groups completed each type of exercise. All training types improved lean body mass and insulin sensitivity, but only high-intensity and combined training improved aerobic capacity and mitochondrial function for skeletal muscle. Increase in muscle strength occurred only modestly with high-intensity interval training but improved with resistance training alone or when added to the aerobic training.

Your brain may be ready for action, even at rest

New York, March 11 (IANS) Even while you are taking rest, your brain networks may be waiting in a state of potentiation to execute even the simplest of behaviours, a finding that may help in improving treatments for neuropsychiatric syndromes, an Indian-origin researcher has showed.

In the study, the researchers studied brain network interactions between two important brain regions: the dorsal anterior cingulate cortex (dACC) -- used for control -- and the supplementary motor area (SMA) -- used for motor movements -- during a simple motor control behaviour, for example tapping forefinger to a visual cue.

The results, published in the journal PLoS One, showed that the network interactions from the SMA to the dACC increased, during the rest periods that alternated between the motor behaviour task.

"These results suggest that directional interactions from the SMA to the dACC during the rest period may in fact potentiate task-related interactions in the opposite direction," said Vaibhav Diwadkar, Professor at Wayne State University in Michigan, US.

For the study, the team used a simple experimental task, having each participant perform a simple motor control behaviour -- tapping their forefinger to a visual cue -- that alternated between behaviour and rest. Brain activity was acquired using functional MRI (fMRI). 

The results reveal aspects not only of normative brain function but may also provide new directions for characterising disordered network interactions in neuropsychiatric syndromes, Diwadkar added.

Microsoft updates Cortana app for iPhone

​New York, March 11 (IANS) US tech giant Microsoft has updated its digital assistant Cortana app for iPhone with a redesigned user interface and new enhancements that offer an improved experience for the Siri competitor.

Italy approves first ever anti-poverty package

​Rome, March 11 (IANS) The Italian parliament on Thursday passed the first ever anti-poverty provision aimed at ensuring a stable economic support to poor families in the country, local media reported on Friday.

Fish eyes may help find cure for blindness

New York, March 11 (IANS) Scientists have discovered a chemical in the zebra fish brain that helps reveal how it regrows its retina, a finding that can potentially cure blindness in humans.

The findings showed that the levels of GABA (gamma aminobutyric acid), a neurotransmitter, best known for its role of calming nervous activity -- drop when the unique self repair process kicks in. 

Thus, blocking the chemical (GABA) could lead to new treatments for AMD (age related macular degeneration), the most common cause of blindness and and retinitis pigmentosa.

The structure of the retinas (the light sensing tissue at the back of the eye) of fish and mammals are basically the same and a reduction in GABA might be the trigger for retinal regeneration, the researchers said.

"Our theory is that a drop in GABA concentration is the trigger for regeneration," said James Patton, Professor at Vanderbilt University, in Tennessee, US.

"If we are correct, then it might be possible to stimulate human retinas to repair themselves by treating them with a GABA inhibitor," Patton added.

In the study, when the scientists injected drugs that kept GABA concentrations in the retinas of newly blinded fish at a high level, they found it suppressed the regeneration process.

After injecting an enzyme that lowers GABA levels in normal fish, they found that the Muller glia (retinal cells) began changing and proliferating, the first stage in the regeneration process.

The Muller glia (which in fish play a key role in regeneration) is a special type of adult stem cell.

When regeneration is triggered in zebrafish, the Muller glia begins proliferating and then differentiating into replacements for the damaged nerve cells.

NASA's 'Europa Clipper' mission to explore Jupiter's moon

Washington, March 10 (IANS) NASA has announced that its upcoming mission to explore the habitability of Jupiter's icy moon Europa will be officially called Europa Clipper.

The mission is being planned for launch in the 2020s, arriving in the Jupiter system after a journey of several years, NASA said in a statement on Friday.

Europa has long been a high priority for exploration because it holds a salty liquid water ocean beneath its icy crust. 

The ultimate aim of Europa Clipper is to determine if Europa is habitable, possessing all three of the ingredients necessary for life -- liquid water, chemical ingredients, and energy sources sufficient to enable biology, the US space agency said. 

Previously, when the mission was still in the conceptual phase, it was sometimes informally called Europa Clipper, but NASA has now adopted that name as the formal title for the mission.

The moniker harkens back to the clipper ships that sailed across the oceans of Earth in the 19th century. 

Clipper ships were streamlined, three-masted sailing vessels renowned for their grace and swiftness. 

These ships rapidly shuttled tea and other goods back and forth across the Atlantic Ocean and around globe.

In the grand tradition of these classic ships, the Europa Clipper spacecraft would sail past Europa at a rapid cadence, as frequently as every two weeks, providing many opportunities to investigate the moon up close. 

The prime mission plan includes 40 to 45 flybys, during which the spacecraft would image the moon's icy surface at high resolution and investigate its composition and the structure of its interior and icy shell.

"During each orbit, the spacecraft spends only a short time within the challenging radiation environment near Europa. It speeds past, gathers a huge amount of science data, then sails on out of there," said Robert Pappalardo, Europa Clipper project scientist at NASA's Jet Propulsion Laboratory in Pasadena, California.

Flire retardant chemicals linked to aggression in kids

New York, March 10 (IANS) Higher exposure to some chemicals added to furniture, electronics and numerous other goods to prevent fires may put kids at increased risk of developing aggression and hyperactivity, says a study.

The researchers studied the behavioural effects of organophosphate-based flame retardants (OPFRs) on young children.

"When we analysed behaviour assessments and exposure levels, we observed that the children who had more exposure to certain types of the flame retardant were more likely to exhibit externalising behaviours such as aggression, defiance, hyperactivity, inattention and bullying," said corresponding author of the study Molly Kile, Associate Professor at Oregon State University in the US. 

Flame retardants are found throughout the built environment in furniture, mattresses, carpeting, electronics, vehicles and more. 

The chemicals are added to the products and are not bound in the material, which causes them to be released into indoor environments.

For this study, published in the journal Environmental Health, the research team recruited 92 children between ages three to five to wear a silicone wristband for seven days to measure exposure to flame retardants.

The researchers had parents or primary caregivers complete questionnaires about socio-demographics and the home environment, and preschool teachers completed behaviour assessments for each participating child. 

In all, researchers had complete data and wristband results for 69 children.

Their analysis showed that all of the children were exposed to some level of flame retardant. 

Children who had higher exposure rates of OFPRs showed less responsible behaviour and more aggression, defiance, hyperactivity, inattention and bullying behaviours.

World's oldest, 152 mn years old crocodile eggs found in Portugal

London, March 10 (IANS) Researchers have found the world's oldest crocodilian eggs that were laid 152 million years ago.

The eggs, discovered in cliffs in Portugal, were laid by close relatives of "true" crocodiles, a group called crocodylomorphs, which according to palaeontologists, had been two metres long.

"The fact that they are from the Late Jurassic period makes these eggs the oldest crocodilian eggs known so far," Joao Russo from the Nova University of Lisbon in Portugal was quoted as saying to the BBC.

"The fossil record tells us that crocodiles and their relatives (forming the larger group of crocodylomorphs) were much more diverse in the past, with different feeding habits, ecological niche distribution or morphology," he added.

The eggs were found in several clutches and appear to be of two different types, the researchers said in the paper published in the journal, Plos One.

"This new discovery from Portugal extends the knowledge of this type of egg by approximately 40 million years," Russo added.

Why do people develop high blood pressure?

Moscow, March 10 (IANS) Early life changes in brain activity and blood flow may be the reason why people tend to develop abnormally high blood pressure, or hypertension, researchers said.

High blood pressure is a condition in which the force of the blood against the artery walls is too high.

It is also often called the silent killer because it typically has no symptoms until after it has done significant damage to the heart and the arteries.

In 90-95 per cent of people, high blood pressure has no identifiable cause, yet it is a risk factor for diseases of the brain, kidneys, heart, eyes, and other parts of the body, said a group of researchers at the Institute of Cytology and Genetics in Russia. 

For the study, published in Experimental Physiology, the team investigated physiological changes in a rat model called ISIAH, short for inherited stress-induced arterial hypertension.

These rats develop high blood pressure at four to six weeks of age, and this is sustained throughout their lifetime.

The researchers compared the high blood pressure rats to a control group with normal blood pressure. 

As the mice in high blood pressure group grew older, changes in rates of blood flow in certain arteries were observed.

In addition, changes were found in the brain activity, specifically a decrease in the prefrontal cortex -- the brain region associated with cognition, decision-making and working memory -- as well as an increase in the hypothalamus -- an area of the brain that controls mood and appetite.

"The study of early physiological changes may help clarify the cause of high blood pressure. Understanding this could help us prevent the disease early on," said led author Alisa Seryapina from the Institute of Cytology and Genetics.