Knowledge Update

​New York, Dec 6 (IANS) Famine may have a lasting impact on the male descendants of its victims, suggests new research focused on survivors of a mass famine that took place in the early 1920s in several rural regions of Russia.

The findings suggest that periods of fasting or starvation may significantly shorten the lifespans of both children and their male descendants.

"A variety of experimental and epidemiological studies have tried to propose that intermittent or periodic fasting, like caloric restriction, may slow the aging process and extend lifespans," said lead researcher Eugene Kobyliansky, Professor at Sackler School of Medicine, Tel Aviv University in Israel.

"But there is also evidence demonstrating that even moderate caloric restriction may not extend but, on the contrary, can shorten the human lifespan," Kobyliansky said.

Past research suggests a strong correlation between telomere dynamics and the processes that determine human ageing and lifespan. 

Telomeres, compound structures at the end of each chromosome that protects the end of the chromosome from deterioration, are the genetic key to longevity. They shorten with every chromosome replication cycle.

The team evaluated telomere lengths in a population-based sample comprised of survivors of the mass famine of the early 1920s and in the survivors' descendants, who originated from Chuvashia, a rural area in the mid-Volga region of Russia. 

In Chuvashia, the proportion of starving inhabitants reached 90 per cent in late March 1922, and mortality among starving peasants reached between 30-50 per cent. The situation only began to improve in April 1923. By the end of that year, the mass famine in Chuvashia was considered over.

The researchers found that here were shorter leukocyte telomeres in men born after 1923 after the mass famine ended than in men born before 1922.

There was a stable inheritance of shorter telomeres by men born in ensuing generations, the findings showed. 

But there was an absence of any correlation between shorter telomeres and women born before or after the event, said the study published in The American Journal of Clinical Nutrition.

New York, Dec 6 (IANS) Pre-school children's skills in patterning, comparing quantities and counting objects were stronger predictors of their math achievement in fifth grade than other skills, researchers said.

The study showed that pre-school math skills supported first-grade math skills, which in turn supported fifth-grade math knowledge. 

By first grade, patterning remained important and understanding written numbers and calculating emerged as important predictors of later achievement.

But, because not all types of math knowledge were equally important, certain early math topics should get more attention than they currently do, the researchers said.

"Counting, calculating, and understanding written numbers already get a lot of attention from teachers and parents, for good reasons," said lead author Bethany Rittle-Johnson, Professor at Vanderbilt University in Tennessee, US. 

"However, comparing quantities may merit more attention in pre-school and patterning knowledge may merit more attention in both pre-school and the early elementary grades," Rittle-Johnson added.

The findings suggest that educators and school administrators may want to consider carefully which areas of math study should they shift attention to as they develop curricula for the early years.

For the study, the team followed 517 low-income children aged between 4-11.

Determining how to help children achieve in math is important, particularly for children from low-income families who often enter school with weaker math knowledge than their peers, the researchers suggested. 

The study appeared in the journal Child Development.

​Dubai, Dec 5 (IANS/WAM) The UAE on Monday highlighted its efforts on biodiversity protection at the 13th meeting of the Conference of the Parties to the Convention on Biological Diversity.

A delegation from the UAE is participating in the meeting in Cancun, Mexico, which is aimed at the conservation of biological diversity, the sustainable use of the components of biological diversity and the fair and equitable sharing of the benefits arising out of the utilisation of genetic resources.

Khalfan Al Suwaidi, Deputy Executive Director of Terrestrial and Marine Biodiversity Sector, who is representing the UAE, said: "The preservation of natural life and its development are top priorities in the UAE and considered as the cornerstones of the country's policy in the field of environmental conservation and development."

Quoting President Sheikh Khalifa bin Zayed Al Nahyan regarding the nation's environment conservation strategy, Al Suwaidi said: "Since its inception, the UAE has been keeping the balance between economic and social development and the preservation of the country's cultural, social and environmental heritage."

"The country has been taking a number of measures, as well as developing relevant laws and legislation regulating professional fishing to preserve, develop and ensure the sustainability of fish stocks," he added.

Toronto, Dec 5 (IANS) Is the very idea of exam giving you stress and negative moods? Take heart, a new study suggests that the occasional bout of bad feelings can actually improve a student's academic performance.

The findings showed that students who were mostly happy during their four years of university but who also experienced occasional negative moods had the highest grade per annum (GPA) at the time of graduation.

In contrast, students who experienced high levels of negative moods and low levels of positive moods often ended up with the lowest GPAs -- a pattern consistent with depressive disorders.

"Students often report feeling overwhelmed and experiencing high levels of anxiety and depressive symptoms. The study shows that we need to teach them strategies to both manage negative emotions and stress in productive ways and to maintain positive emotional experiences," said Erin Barker, Professor at Concordia University in Quebec, Canada.

For the study, Barker and her team worked with 187 first-year university students. They looked at the students' response patterns to better understand how experiences of positive and negative emotions occurred over time.

The study also demonstrated that both negative and positive emotions play a role in our successes.

"We often think that feeling bad is bad for us. But if you're generally a happy person, negative emotions can be motivating. They can signal to you that there is a challenge that you need to face. Happy people usually have coping resources and support that they draw on to meet that challenge," Barker said, in the study published in the journal Developmental Psychology.

​London, Dec 5 (IANS) Women with dementia receive less health monitoring and take more potentially harmful medication than men with dementia, says a study.

The Britain-based study found that women were at particular risk of staying on anti-psychotic or sedative medication for longer. 

This might be because they have fewer appointments where their treatment can be reviewed, the study said.

"As women tend to live longer than men, they are more likely to live alone without a family carer to help them access healthcare," said lead researcher Claudia Cooper from University College London.

"Perhaps because of this, they are more at risk of missing out on medical help that might help them stay well for longer. We found that women were more likely to be on psychotropic drugs -- sedatives or anti-psychotics -- which can be harmful in the long term and may not be appropriate," Cooper said.

"Women tended to stay on such drugs for longer, perhaps because they have fewer check-ups to see if the drugs were still needed," Cooper explained.

The researchers analysed the records of 68,000 dementia patients and 259,000 people without dementia to compare their access to healthcare services, using The Health Improvement Network (THIN) database. 

Overall, people with dementia received less medical care than those without even though they are more vulnerable to physical and mental illnesses, showed the study published in the journal Age and Ageing.

Compared to men with dementia, women with dementia had lower rates of surgery consultations, of annual blood pressure monitoring and of annual weight monitoring .

Men with dementia were less likely to be taking psychotropic medication than women with dementia. 

"Women with dementia who live on their own may need additional support accessing healthcare services," Cooper said.

"Improving access to healthcare and reducing psychotropic drug use in people with dementia, especially women, could help them to live well with dementia for longer," Cooper noted.

New York, Dec 5 (IANS) A person's bones may act as one of the earliest indicators of brain degeneration in Alzheimer's disease, researchers have found.

Alzheimer's is a progressive disease that destroys memory and other important mental functions.

The study showed that early reduction in bone mineral density that occur in a preclinical model of Alzheimer's are due to degeneration in an area of the brainstem.

The brainstem is a region that controls mood, sleep and metabolism -- that produces the majority of the brain's serotonin -- a neurochemical that controls our mood and sleep.

The reduced bone mineral density, which sometimes leads to osteoporosis, translates to increased bone fracture risk, decreased quality of life, and increased mortality for Alzheimer's patients. 

Further, early bone loss and serotonin deficiency in Alzheimer's may tell us something very important about how we approach diagnosis and treatment, the researchers noted.

"Routine assessment of bone density could serve as a useful biomarker for Alzheimer's risk in ageing population," said lead author Christine Dengler-Crish, Assistant Professor at Northeast Ohio Medical University(Neomed) in the US. 

"The findings of this study motivate us to explore the serotonin system as a potential new therapeutic target for this devastating disease," Dengler-Crish added.

The study is forthcoming in the Journal of Alzheimer's Disease.

​New York, Dec 5 (IANS) Frequent casino goers probably know it already, but a new study has found evidence that our decisions tend to be quicker and less accurate as the day wears on.

The findings based on decisions taken by chess players hold true irrespective of whether someone is in the habit of waking up early in the morning or later in the day.

"During the morning, players adopt a prevention focus policy (slower and more accurate decisions) which is later modified to a promotion focus (faster but less accurate decisions), without daily changes in performance," the study said.

Diego Golombek from the National University of Quilmes in Argentina and colleagues said that human behaviour and physiology exhibit fluctuations in a single day. 

The researchers examined the quality of moves in more than one million games of chess in an online database. They charted the decisions of 99 prolific players by gauging the time they took for each move and its usefulness in leading to a victory, Science magazine reported.

Understanding whether decision-making in real-life situations depends on the relation between time of the day and an individual's diurnal preferences has both practical and theoretical implications. 

However, answering this question has remained elusive because of the difficulty of measuring precisely the quality of a decision in real-life scenarios. 

The researchers choose chess players for the study, as in a chess game, every player has to make around 40 decisions using a finite time budget and both the time and quality of each decision can be accurately determined. 

The researchers were not surprised to find that early risers preferred to play more games in the morning, whereas night owls, or those who generally stay up late at night, were active at dusk and beyond. 

But regardless of their diurnal preferences, the players took longer but better decisions in their early games. Their decisions became quicker and less effective by evening, said the study to be published in a forthcoming issue of the journal Cognition.

​New York, Dec 4 (IANS) Researchers have found that the vapours which are produced after e-liquid flavourings are heated inside e-cigarettes, are toxic.

According to a study, reported in the ACS journal Environmental Science and Technology, when e-liquid flavourings are heated inside electronic nicotine-delivery systems, the flavourings break down into toxic compounds at levels that exceed occupational safety standards.

The researchers analysed vapours created from both unflavoured and flavoured e-liquids loaded into three popular types of e-cigarettes. 

The results showed that in general, one puff of flavoured vapour contained levels of aldehydes exceeding the safe thresholds for occupational exposure -- set by the American Conference of Governmental Industrial Hygienists -- by factors of 1.5 to 270. Vapours from unflavoured e-liquids contained aldehydes at significantly lower levels.

Electronic cigarettes were first introduced to the market in 2003 and health officials have been tracking usage and studying potential health effects.

A 2015 survey by the National Centre for Health Statistics reported that 3.7 per cent of adults used the devices regularly and 12.6 per cent had tried them at least once.

​New York, Dec 4 (IANS) A team of researchers has created a new method to analyse big data that better predicts outcomes in health care, politics and other fields.

In an effort to reduce the error rate with methods like using a significance-based criterion for evaluating variables to find highly predictive variables, researchers at Princeton, Columbia and Harvard universities in the US proposed a new measure called the influence score, or I-score, to better measure a variable's ability to predict.

In their study, to be published in journal Proceedings of the National Academy of Sciences, researchers found that the I-score is effective in differentiating between noisy and predictive variables in big data and can significantly improve the prediction rate.

"The practical implications are what drove the project, so they are quite broad," lead author Adeline Lo said.

"That the I-score fares especially well in high dimensional data and with many complex interactions between variables is an extra boon for the researcher or policy expert interested in predicting something with large dimensional data," Lo, who is a postdoctoral researcher in Princeton's Department of Politics, added.

The I-score improved the prediction rate in breast cancer data from 70 per cent to 92 per cent. 

The I-score can be applied in a variety of fields, including terrorism, civil war, elections and financial markets, the researchers said.

​New York, Dec 4 (IANS) While buying toys, parents and grandparents should consider the child's interests, not their gender because limiting choice of toys according to gender can fuel stereotypes, suggests new research.

Clues to the continued dominance of men in the STEM (science, technology, engineering, and mathematics) fields -- and the reason nurturing often comes more easily to women -- can be found in the children's toy department, said sociologist Elizabeth Sweet from California State University, Sacramento, US.

"When we wall off the toys that develop spatial skills or are devoted to science and say, 'These are only for boys,' and we wall off the toys that develop empathy and verbal skills and say, 'These are only for girls,' it severely limits how children develop," Sweet said in a university statement.

"If kids aren't exposed to the kinds of toys and play that help them develop those skills, they may not be as good at them over time. But even more insidious is that it reinforces the stereotype that boys are good at science and math, and girls are not. It pushes women and girls out of that field, because they think it's not for them," she explained.

Sweet believes that making STEM toys pink, as proposed by some toy manufacturers, would not help much.

"I think that's the wrong approach," Sweet said.

"I think that plays up the stereotype that girls are so different that they need a special kind of STEM toys," noted.

"Research shows that different kinds of toys help children to develop different kinds of skills," she said.

"For instance, building blocks are great for building spatial skills. Playing with dolls is really good for developing language skills and nurturing abilities. All of those skills are essential for a fully functioning human," Sweet pointed out.