Knowledge Update

​London, July 6 (IANS) Infections with two types of malaria parasite lead to greater health risks because one species helps the other to thrive, new research has found.

The researchers sought to understand what happens when the two most common malaria parasites cause infection at the same time, as they are known to attack the body in different ways.

They found that one type of parasite leads to the second species being provided with more of the resources it needs to prosper.

In people, a parasite known as P. falciparum infects red blood cells of all ages, while another - P. vivax - attacks only young red blood cells.

"Our findings also challenge ideas that one species will outcompete the other, which explains why infections involving two parasite species can pose a greater health risk to patients," said one of the researchers Sarah Reece, Professor at University of Edinburgh in Scotland.

Experiments in mice with equivalent malaria parasites showed that the body's response to the first infection produces more of the type of red blood cell that the second parasite needs.

In response to the first infection, millions of red blood cells are destroyed. The body responds by replenishing these cells. These fresh cells quickly become infected by the second type of parasite, making the infection worse, the researchers said.

The finding could explain why infections with both P. falciparum and P. vivax in people often have worse outcomes for patients than single infections, the team noted.

Until recently, it was unclear how two parasite species interacted during co-infections.

The study, published in the journal Ecology Letters, was carried out in collaboration with the University of Toronto. ​

​New York, July 6 (IANS) Ditching homemade food for that king size burger and French fries can add not only extra kilos around your belly but may also increase the risk of developing diabetes, a study has warned.

Individuals who often ate from outside, typically fast food were more prone to gain weight -- a major cause for developing Type 2 diabetes, the researchers said.

Concerns have been raised that such people have a diet that is rich in energy but relatively poor in nutrients -- this could lead to weight gain, which is, in turn, associated with an increased risk of Type 2 diabetes, said Qi Sun from the Harvard T.H. Chan School of Public Health.

The findings showed that the people who consumed five-seven evening meals prepared at home during a week had a 15 per cent lower risk of Type 2 diabetes than those who consumed two such meals or fewer in a week. 

A smaller, but still statistically significant, reduction was apparent for those who consumed more midday meals prepared at home. 

Well-established diabetes prevention strategies include behavioural interventions aimed at increasing exercise and improving dietary habits.

The nutritional and lifestyle benefits of consuming meals prepared at home could contribute to these diabetes prevention efforts, the researchers suggested.

For the study, appearing in the journal PLOS Medicine, the team employed large prospective datasets in which US health professionals -- both men and women--were followed-up for long periods, with rigorous collection of data on health indicators, including self-reported information on eating habits and occurrence of diabetes.

New York, July 6 (IANS) Researchers have discovered that a protein in urine samples correlates with the presence and severity of Parkinson's disease.

The biomarker may act as a possible guide for future clinical treatments and a monitor of the efficacy of potential new Parkinson's drugs in real time during treatment.

"Nobody thought we'd be able to measure the activity of this huge protein called LRRK2 (pronounced lark two) in biofluids since it is usually found inside neurons in the brain," said Andrew West, Professor at the University of Alabama at Birmingham in the US.

For more than five years, urine and cerebral-spinal fluid samples from patients with Parkinson's disease have been locked in freezers in the National Institute of Neurological Disorders and Stroke (NINDS) National Repository.

They were stored with the expectation they might someday help unravel the still hidden course of this slow acting neurodegenerative disease.

"New biochemical markers like the one we've discovered together with new neuroimaging approaches are going to be the key to successfully stopping Parkinson's disease in its tracks,” West said. 

"I think the days of blindly testing new therapies for complex diseases like Parkinson's without having active feedback both for 'on-target' drug effects and for effectiveness in patients are thankfully coming to an end," West noted.

The findings appeared in the journal Movement Disorders.

A biomarker helps physicians predict, diagnose or monitor disease, because the biomarker corresponds to the presence or risk of disease, and its levels may change as the disease progresses. 

Validated biomarkers can aid both preclinical trial work in the laboratory and future clinical trials of drugs to treat Parkinson's. ​

​London, July 6 (IANS) The first-ever record of a tumourous facial swelling found in a fossil has been discovered in the jaw of an estimated 69 million-year-old dwarf dinosaur, say researchers.

The fossil was discovered in the 'Valley of the Dinosaurs' in the Dinosaurs Geopark in Transylvania, western Romania. 

The non-cancerous facial tumour found on Telmatosaurus -- a type of primitive duck-billed dinosaur and also known as a hadrosaur -- had been previously seen in humans, mammals and some modern reptiles, but never before encountered in fossil animals.

"This discovery is the first ever described in the fossil record and the first to be thoroughly documented in a dwarf dinosaur,” said Kate Acheson, doctoral student at the University of Southampton in Britain.

“Telmatosaurus is known to be close to the root of the duck-billed dinosaur family tree, and the presence of such a deformity early in their evolution provides us with further evidence that the duck-billed dinosaurs were more prone to tumours than other dinosaurs," Acheson added.

The study was published in the journal Scientific Reports.

Scans taken of the Telmatosaurus fossil suggested that the dinosaur suffered from a condition known as 'ameloblastoma' -- a tumourous, non-cancerous growth known to afflict the jaws of humans and other mammals and some modern reptiles, too.

It is unlikely that the tumour caused the dinosaur any serious pain during its early stages of development, just as in humans with the same condition, but this particular dinosaur died before it reached adulthood, the researchers said, though they could not ascertain the cause of its death. 

"The tumour in this dinosaur had not developed to its full extent at the moment it died, but it could have indirectly contributed to its early demise," Zoltan Csiki-Sava from the University of Bucharest in Romania noted. ​

​Bangalore, July 4 (IANS) Taking the burgeoning gaming market to a new height, Global PC, tablet and smartphone maker Lenovo on Monday launched a new gaming portfolio for the millennial gamers in India. The thin and portable Rs 99,990 Lenovo Y700 Windows 10 is packed with an in-built 1 TB + 128 GB SSD and runs on standard volt Intel Core i7 Skylake CPU with Turbo Boost abilities. "The new Y700 is testimony to Lenovo’s constant innovation and pursuit to create new categories that enhance the consumer experience. The sleek Lenovo Y700 offers the experience, performance and versatility that gamers look for,” said Bhaskar Choudhuri, Director, Marketing Lenovo India, in a statement. For gamers on the go, this machine has plenty of horsepower to swap between graphics-intensive game time and rich-media software like Photoshop and CorelDraw. The machine comes with latest 4GB NVIDIA graphics, powerful Dolby audio JBL speakers, a subwoofer and an optional 10-point multi-touch display or Intel’s RealSense Camera (on the 15-inch laptop) that further enhances the gaming and multimedia experience. The “Optimised Thermal Cooling” technology keeps the Y700 stay cool even in intense on-screen actions. Along with the Y700, customers will also get a free Lenovo Y Gaming Backpack that fits up to a 17.3-inch laptop, includes padded pockets, a protective hard shell compartment and a chest strap for extra carrying support. As a special launch offer, the some cool gaming accessories worth Rs 12999 are available to customers at the price of Rs 2499 that include Lenovo Y Gaming Surround Sound Headset, Lenovo Y Gaming Precision Mouse and Lenovo Y Gaming Mechanical Switch Keyboard. The gaming portfolio is available on Lenovo's thedostore.com.​

​New Delhi, July 3 (IANS) A two-day meeting of the BRICS Working Group on 'Energy Saving and Energy Efficiency' will be held on July 4-5 in Visakhapatnam, an official said here on Sunday.

​London, July 2 (IANS) Want to stop craving for mouth-watering desserts? No worries as eating a powdered food supplement -- based on a molecule produced by bacteria in the gut -- can reduce craving for high-calorie foods such as chocolates, cakes and pizzas.

Sscientists have developed an ingredient called inulin-propionate ester to investigate the role of propionate molecule produced by the gut microbiota in human health.

For the study, the team analysed 20 volunteers who consumed a milkshake that either contained inulin-propionate ester or a type of fibre called inulin.

After drinking milkshakes, the participants underwent an MRI scan where they were shown pictures of various low or high calorie foods such as salad, fish and vegetables or chocolate, cake and pizza.

The findings showed that when the volunteers drank the milkshake containing inulin-propionate ester, they had less activity in areas of their brain linked to reward -- but only when looking at the high-calorie foods.

"The study shows that this supplement can decrease activity in brain areas associated with food reward at the same time as reducing the amount of food they eat," said Gary Frost, professor at Imperial College London.

Further, the volunteers were found to rate the high-calorie foods as less appealing.

In another experiment, the volunteers were given a bowl of pasta with tomato sauce and asked to eat as much as they like.

However, after drinking the inulin-propionate ester, the participants ate 10 per cent less pasta than when they drank the milkshake that contained inulin alone.

"This study shows that altering how the gut works can change not only appetite in general, but also change how the brain responds when they see high-calorie foods and how appealing they find the foods to be," noted another researcher Tony Goldstone from Imperial College London.

“Using inulin-propionate ester as a food ingredient may help prevent weight gain as it could reduce the urge to consume high calorie foods," suggested Claire Byrne from Imperial College London.

Some people's gut bacteria may naturally produce more propionate than others, which may be why some people seem more naturally predisposed to gain weight, said the paper published in the American Journal of Clinical Nutrition.​

London, July 3 (IANS) Does your boss always punish you? If so, he or she may be afraid of losing the power and position, reveals a study.

The findings showed that distrust is the main reason why leaders impose punishments on the people over whom they have power.

Afraid of losing their power, the leaders use punishments as deterrents and to ensure that similar rule-breaking behaviour never happens again.

“Leaders expect other people not to obey the rules and punish them on the basis of this distrust,” said Marlon Mooijman, psychologist at Leiden University in the Netherlands.

Further, leaders are afraid that if they are too trusting of others, this trust can be abused. This would then, of course, threaten their position.

Unfortunately, punishments of this kind do not have the desired effect. "We see that some power systems can actually exacerbate the problems. This particularly relates to issues such as unethical behaviour, plagiarism and fraud," the researchers explained.

"When people feel distrusted, they are less likely to obey the rules. They see this assumption on the part of the leaders as a sign of disrespect. It also violates an implicit social contract: If you treat me well, I will act accordingly," Mooijman added.

For the study, the team conducted experiments with groups of students, who were temporarily assigned to a manager position. They were asked to write about an incident in which they felt very powerful, or conversely very powerless.

They then had to decide how someone who had committed plagiarism should be punished.

Students who had been made to feel powerful were found to favour punishments designed to make an example of the offenders.

The deterrent aspect was important, and some were even prepared to publicly name the people who had committed plagiarism.

New York, July 3 (IANS) The brain activity generated while relaxing is likely to indicate individuals who can learn new languages faster, says a research.

The findings showed that a five-minute measurement of resting-state brain activity predicted how quickly adults picked up a second language.

“The way someone's brain functions while at rest can predict 60 per cent of their capacity for learning a second language,” said lead author Chantel Prat, Associate Professor at the University of Washington.

The patterns of resting-state brain waves reflect synchronised firing of large networks of neurons and can determine subsequent language learning rate.

The findings showed that the larger the networks in "beta" frequencies -- brain frequencies associated with language and memory, the faster was the learning.

"This is vital brain function research that could enable the military to develop a more effective selection process of those who can learn languages quickly," said Ray, a program officer in Office of Naval Research's (ONR) Warfighter Performance Department, who oversees the research.

"This is especially critical to the intelligence community, which needs linguists fluent in a variety of languages, and must find such individuals rapidly," Perez added.

For the study, 19 participants -- adults between the ages of 18 and 31, with no previous experience learnt French over eight weeks for 30-minute French lessons delivered through an immersive, virtual-reality computer program.

For five minutes before and after the eight-week curriculum, the team had participants sit still, close their eyes, breathe deeply and wear an EEG (electroencephalogram) headset measuring resting-state brain activity from the cerebral cortex--an area of the brain crucial to memory, attention and perception.

The results showed that those with the larger "beta" networks learned French twice as quickly.

"By studying individual differences in the brain, we're figuring out key constraints on learning and information processing, to develop ways to improve language mastery," said Prat.​

​New York, July 3 (IANS) Auricular acupuncture has a greater overall impact on headache-related quality of life (QoL) than did traditional Chinese acupuncture, says a new US study.

The study, published in Medical Acupuncture journal, compared the effectiveness of usual care alone to usual care plus either auricular or traditional Chinese acupuncture in treating patients with headaches due to a previous traumatic brain injury (TBI) and showed a significant improvement in headache-related quality of life (QoL) with the addition of acupuncture. 

The study was conducted on previously deployed members of the US military who had mild to moderate TBI and headaches. Chronic or recurrent headache is reported by 80 per cent of service members with TBI.

"Chronic concussion headaches are a clinical challenge. Acupuncture appears promising to avoid the opioid gateway for these patients," says Richard C. Niemtzow, director, US Air Force Acupuncture and Integrative Medicine Center.