Knowledge Update

London, Feb 23 (IANS) Would you like to know what does the future hold for you? If yes, you may have only a few company. A new study shows that given the chance to see into the future, most people would rather not know what life has in store for them -- whether it brings good things or bad.

"In Greek mythology, Cassandra, daughter of the King of Troy, had the power to foresee the future. But, she was also cursed and no one believed her prophecies," said the study's lead author Gerd Gigerenzer from Max Planck Institute for Human Development in in Berlin, Germany. 

"In our study, we've found that people would rather decline the powers that made Cassandra famous, in an effort to forgo the suffering that knowing the future may cause, avoid regret and also maintain the enjoyment of suspense that pleasurable events provide," Gigerenzer said.

The findings, published in the journal Psychological Review, are based on two studies involving more than 2,000 adults in Germany and Spain.

The study found that 85 to 90 per cent of people would not want to know about upcoming negative events, and 40 to 70 percent preferred to remain ignorant of upcoming positive events. 

Only one percent of participants consistently wanted to know what the future held. 

The researchers also found that people who prefer not to know the future are more risk averse and more frequently buy life and legal insurance than those who want to know the future. 

This suggests that those who choose to be ignorant anticipate regret, Gigerenzer said. 

The length of time until an event would occur also played a role. Deliberate ignorance was more likely the nearer the event. 

For example, older adults were less likely than younger adults to want to know when they or their partner would die, and the cause of death. 

"Not wanting to know appears counter-intuitive and may raise eyebrows, but deliberate ignorance, as we've shown here, doesn't just exist; it is a widespread state of mind," Gigerenzer said.

​London, Feb 23 (IANS) Injecting a particular weight loss drug in combination with diet and exercise may reduce risk of diabetes by 80 per cent in individuals with obesity and prediabetes, a study said.

The results of the international clinical trial showed that liraglutide promoted weight loss by interacting with the areas of the brain that control appetite and energy intake.

Published in the journal The Lancet, the results showed that three years of continuous treatment with once-daily liraglutide 3.0 mg, in combination with diet and increased physical activity, reduced the risk of developing the Type 2 diabetes.

In fact, in 60 per cent of those patients with borderline diabetes the condition was reversed, and patients returned to healthy blood sugar levels, the study showed.

"Liraglutide promotes weight loss by activating brain areas that control appetite and eating, so that people feel fuller sooner after meals and their food intake is reduced," said Carel le Roux, Professor at Imperial College London. 

"Although liraglutide's role in weight loss is well known, this is the first time it has been shown to essentially reverse prediabetes and prevent diabetes, albeit with the help of diet and exercise," le Roux added.

Of the patients who did go on to develop diabetes, those who were given liraglutide, took nearly three times longer to develop the disease. 

In addition, liraglutide also helped patients lose seven per cent body weight compared to only two per cent in the placebo group, the researchers said.

"Liraglutide 3.0 mg can provide us with a new therapeutic approach for patients with obesity and prediabetes," explained John Wilding, Professor at the University of Liverpool.

For this obesity and prediabetes trial, the team followed 2,254 adults with prediabetes at 191 research sites in 27 countries worldwide. 

The participants were randomly allocated either liraglutide 3.0 mg or a placebo delivered by injection under the skin once daily for 160 weeks. 

They were also placed on a reduced calorie diet and advised to increase their physical activity.

​Washington, Feb 23 (IANS) In a major boost to the search for alien life outside our solar system, astronomers have spotted the first known system of seven Earth-size planets around a single star, NASA said.

All of these seven planets could have liquid water -- key to life as we know it -- under the right atmospheric conditions, but the chances are highest with three of the plants which are located in the habitable zone, according to the researchers.

"This discovery could be a significant piece in the puzzle of finding habitable environments, places that are conducive to life," said Thomas Zurbuchen, Associate Administrator of NASA's Science Mission Directorate in Washington. 

At about 40 light-years (235 trillion miles) from Earth, the system of planets is relatively close to us, in the constellation Aquarius. 

Because they are located outside of our solar system, these planets are scientifically known as exoplanets.

This exoplanet system is called TRAPPIST-1, named for The Transiting Planets and Planetesimals Small Telescope (TRAPPIST) in Chile. 

In May 2016, researchers using TRAPPIST announced they had discovered three planets in the system. 

Assisted by several ground-based telescopes, including the European Southern Observatory's Very Large Telescope, NASA's Spitzer space telescope confirmed the existence of two of these planets and discovered five additional ones, increasing the number of known planets in the system to seven.

Using Spitzer data, the team precisely measured the sizes of the seven planets and developed first estimates of the masses of six of them, allowing their density to be estimated.

Based on their densities, all of the TRAPPIST-1 planets are likely to be rocky, according to the new results published on Wednesday in the journal Nature

Further observations will not only help determine whether they are rich in water, but also possibly reveal whether any could have liquid water on their surfaces. 

The mass of the seventh and farthest exoplanet has not yet been estimated. But scientists believe it could be an icy, "snowball-like" world, but further observations are needed.

The discovery of the seven exoplanets sets a new record for greatest number of habitable-zone planets found around a single star outside our solar system. 

"The seven wonders of TRAPPIST-1 are the first Earth-size planets that have been found orbiting this kind of star," said Michael Gillon, lead author of the paper and the principal investigator of the TRAPPIST exoplanet survey at the University of Liege, Belgium. 

"It is also the best target yet for studying the atmospheres of potentially habitable, Earth-size worlds," Gillon said.

In contrast to our sun, the TRAPPIST-1 star - classified as an ultra-cool dwarf - is so cool that liquid water could survive on planets orbiting very close to it, closer than is possible on planets in our solar system. 

All seven of the TRAPPIST-1 planetary orbits are closer to their host star than Mercury is to our sun, the researchers said.

​Canberra, Feb 23 (IANS) Australian engineers have created an advanced microscope using a beefed-up "barcode scanner", which they believe will help doctors better analyse complex medical conditions such as cancer.

Engineers from the Australian National University (ANU) said the microscope can film moving blood cells and neurons in living animals, something which they say will help doctors and scientists to research complex blood disorders, Xinhua news agency reported.

Steve Lee, a biomedical optics engineer at the ANU, said the microscope used technology similar to retail barcode scanners and office laser printers.

"Scientists can use our new microscope to analyse complex medical problems ranging from blood disorders and cancer to neurological disorders," Lee said in a statement released on Thursday.

"The microscope can speed up or slow down to capture the slow moving cells in a blood stream or live neurons firing rapidly in the brain, making it much more flexible than other microscopes on the market."

In traditional, "supermarket-style", barcode scanners, a laser beam bounces off a spinning polygon mirror, allowing it to scan across a sample very quickly. The scanner detects the unique sequence of each barcode to identify each certain product.

Lee said the ANU microscope used a more powerful laser beam as the light source and up to 36 mirror facets to "scan the laser beam across the biological sample in a few thousandths of a second".

"We achieve the same imaging resolution of conventional scanning microscopes on the market but at double the speed," he said.

"The innovation here is that we modernised the polygon mirror microscopy system with advanced electronics and software controls to enable real-time imaging applications, with up to 800 frames per second."

Washington, Feb 22 (IANS) NASA's Fermi gamma-ray space telescope has found a signal at the centre of the neighbouring Andromeda galaxy that could be coming from dark matter, an unknown substance that makes up most of the universe, according to a study.

The gamma-ray signal is similar to one seen by Fermi at the centre of our own Milky Way galaxy.

"Our galaxy is so similar to Andromeda, it really helps us to be able to study it, because we can learn more about our galaxy and its formation," said study co-author Regina Caputo, a research scientist at NASA's Goddard Space Flight Centre in Greenbelt, Maryland. 

Gamma rays are the highest-energy form of light, produced by the universe's most energetic phenomena.

They are common in galaxies like the Milky Way because cosmic rays, particles moving near the speed of light, produce gamma rays when they interact with interstellar gas clouds and starlight.

Surprisingly, the latest Fermi data shows the gamma rays in Andromeda -- also known as M31 -- are confined to the galaxy's centre instead of spread throughout, said the study to be published in an upcoming issue of The Astrophysical Journal.

To explain this unusual distribution, scientists are proposing the emission may come from several undetermined sources. One of them could be dark matter.

"We expect dark matter to accumulate in the innermost regions of the Milky Way and other galaxies, which is why finding such a compact signal is very exciting," said led scientist Pierrick Martin, an astrophysicist at the National Center for Scientific Research and the Research Institute in Astrophysics and Planetology in Toulouse, France. 

"M31 will be a key to understanding what this means for both Andromeda and the Milky Way," Martin said.

Another possible source for this emission, according to the scientists, could be a rich concentration of pulsars in M31's centre.

Sydney, Feb 21 (IANS) Australia's New South Wales state will focus on better preparing students for university and employment in a major overhaul of its school curriculum.

New South Wales on Tuesday unveiled changes to its high school syllabus for the first time in 18 years, the BBC reported.

The new focus eschews "social context" teaching -- which had drawn criticism -- for more in-depth, critical thinking.

It comes after an international study in December showed Australia's maths and science ranking had tumbled.

The changes address recent criticism over a lack of rigour, said Tom Alegounarias, the head of the state's Education Standards Authority.

"We reviewed the whole (syllabus), we looked at what the community is demanding for now and in the future," Alegounarias told the Australian Broadcasting Corporation.

"The major shift is towards greater depth, rigour, and mastery of content learning."

However, education officials said the concerns were addressed.

Maths will now include more statistics and algorithms, such as those used by internet search engines.

In English, texts will no longer be studied through themes like "journey" or "discovery" but examined for their individual merit.

In history, subjects such as the Enlightenment and the Industrial Revolution will be explored in depth, rather than focusing on a breadth of topics.

The new curriculum will be introduced from next year, the BBC added.

New York, Feb 21 (IANS) Adolescents suffering from trauma and stress are likely to have impairment in the ability to recognise facial expressions that is critical for social functioning and communicating emotions, researchers say.

The findings showed that adolescents with post-traumatic stress disorder (PTSD) symptoms are more likely to misidentify sad and angry faces as fearful.

"Our findings suggest that exposure to stress and trauma can have acute emotional impacts that simply translate to misidentification of important affective cues," said lead author Shabnam Javdani, Assistant Professor at New York University - Steinhardt in the US.

"Fear is particularly relevant for understanding PTSD, as the disorder has been associated with a 'survival mode' of functioning characterised by an overactive fight-or-flight response and increased threat perception," Javdani added.

In contrast, teens with conduct disorder -- a group of behavioural and emotional problems characterised by callousness or aggression towards others -- were more likely to misidentify sad faces, but did not have trouble recognising angry or fearful faces. 

Conduct disorder symptoms were associated with mistaking sadness for anger, suggesting that youth with higher levels of conduct disorder interpret sad faces as angry and may be less effective at recognising others' sadness, pain and suffering.

"Difficulty interpreting displays of sadness and misidentifying sadness as anger may contribute to the impaired affective bonding, low empathy, and callous behaviour observed in teens with conduct disorder," Javdani said.

For the study, published in the journal Child and Adolescent Mental Health, the team examined 371 teens, ages 13-19, to understand the effects of PTSD and conduct disorder symptoms on how youth with emotional and behaviour problems process facial expressions. 

Enhancing the accuracy of recognising facial expressions may be an important treatment goal for youth with symptoms of PTSD and conduct disorder, the researchers said.

​London, Feb 21 (IANS) Offering a glimmer of hope for people suffering from chronic nerve pains, researchers have found that a novel substance inhibits the pain effectively and is well tolerated.

The standard treatment for this chronic nerve pain, known as trigeminal neuralgia, a condition that can lead to acute pain in the teeth or facial area, is associated with burdening side effects. 

In this study, published in the journal Lancet Neurology, the substance, BIIB074, was found to reduce the pain to a tolerable level.

"Unlike conventional drugs, which often cause tiredness and concentration problems, BIIB074 was not only effective, but also very well tolerated," said one of the researchers, Dominik Ettlin, a dental specialist at University of Zurich in Switzerland. 

"We will now test the new substance in a lot more subjects during the next study phase, which will reveal whether the new hope for more effective pain relief is justified," he added.

Bouts of pain in people with trigeminal neuralgia can be triggered by touch, such as shaving, putting on make-up, showering, talking and tooth brushing, or even a gust of wind. 

The cause is usually an irritation of the trigeminal nerve, the cranial nerve responsible for the sensory innervation of the facial area, parts of the scalp, and the oral cavity.

Pain signals reach the brain via the activation of sodium channels located in the membranes of nerve cells. 

The sodium channel "1.7" is frequently expressed on pain-conducting nerves and higher pain intensity is linked to higher channel activity. 

Blocking this sodium channel inhibits the pain. 

In trigeminal neuralgia, the nerve damage is presumed to be at the base of the skull. However, this region is hard to reach by local injections and therefore requires drug treatment.

In this study, the researchers found that the more active this sodium channel gets, the stronger it is blocked by the novel substance BIIB074. 

By contrast, currently available medications block the sodium channel irrespective of the nerve activity, which commonly results in burdening side effects, the study said.

​New York, Feb 21 (IANS) Love to eat fish and other seafood? Be careful, as eating mercury-rich fish such as shark and swordfish may increase the risk of developing amyotrophic lateral sclerosis (ALS) -- that takes away the ability of nerve cells to interact with the body's muscles -- a study has warned.

Mercury -- a heavy metal known to be toxic at high levels, causing brain, heart, kidney, lung and immune system damage -- is found high in swordfish and shark, while salmon and sardines typically have lower levels. 

However, the study does not suggest a higher risk of ALS -- also referred to as Lou Gehrig's disease -- from general consumption of seafood.

"For most people, eating fish is part of a healthy diet. But questions remain about the possible impact of mercury in fish," said Elijah Stommel from Dartmouth College in New Hampshire, US.

For the study, the team surveyed 518 people, 294 of whom had ALS and 224 of whom did not and the frequency that the participants reported eating fish with high mercury levels. 

Researchers also measured the levels of mercury found in toenail samples of participants with ALS.

The results, presented at the American Academy of Neurology's 69th Annual Meeting in Boston, revealed that 61 per cent people had a 25 per cent estimated annual mercury intake. These were at double the risk for ALS compared to those with lower levels.

The findings does not negate the fact that eating fish provides many health benefits.

But, people should choose species that are known to have a lower mercury content and avoid consuming fish caught in waters where there is mercury contamination, the researchers suggested.

New York, Feb 20 (IANS) People living in big cities with a large density of population are more likely to prefer long-term romantic relationships, have fewer children and invest more in education, suggesting that they value quality over quantity, researchers say.

The findings showed that urban citizens are more likely to adopt a 'slow life strategy', contrary to the popular notion that crowded places are chaotic and socially problematic.

"People who live in dense places seem to plan for the future more, prefer long-term romantic relationships, get married later in life, have fewer children and invest a lot in each child. They generally adopt an approach to life that values quality over quantity," said lead author Oliver Sng, a postdoctoral fellow at the University of Michigan. 

In environments where population density is low and there is thus relatively little competition for available resources, there are few costs but lots of advantages to adopting a 'fast' strategy.

On the other hand, when the environment gets crowded, individuals have to compete vigorously with others for the available resources and territory, the researchers said.

"So a slow strategy -- in which one focuses more on the future and invests in quality over quantity -- tends to enhance the reproductive success of individuals in high density environments," added Steven Neuberg Professor at Arizona State University. 

For the study, published in the Journal of Personality and Social Psychology, the team used data from nations around the world and the 50 US states. 

In a series of experiments -- for example, in which people read about increasing crowdedness or heard sounds of a crowded environment -- they found that perceptions of crowdedness cause people to delay gratification and prefer slower, more long-term, mating and parenting behaviours.